Cushing's Syndrome

Cushing’s Syndrome is a rare disease caused by prolonged exposure to elevated levels of either endogenous glucocorticoids or exogenous glucocorticoids. ST-002 is uniquely well suited to address the hyperglycemia and NASH that characterize Cushing’s Syndrome. Despite the apparently benign character of the disease, Cushing’s syndrome is associated with increased mortality and multisystem morbidity. Cushing’s Syndrome patients also suffer from other severe conditions like

• 40-75% Diabetes

• >85% Obesity

• 20% NASH/NAFLD

 

Mechanism of Action ST-002

• Inhibition of Glucose-6-Phosphate Dehydrogenase

• Potent Anti-Glucocorticoid